Bone as an endocrine organ pdf
نویسندگان
چکیده
These advances point to the skeleton as an endocrine organ that modulates glucose tolerance and testosterone production by secretion of a bone-specific.Bone as an endocrine organ. 1 Division of Nephrology Endocrinology, Department of Medicine, University of Tokyo. These new endocrine pathways and discuss their physiological. Recognition of bone as a true endocrine organ represents a fertile area for. Hormone leptin is a major inhibitor of bone remodelling, led to the hypothesis.
منابع مشابه
Bone and Muscle Endocrine Functions: Unexpected Paradigms of Inter-organ Communication
Most physiological functions originate with the communication between organs. Mouse genetics has revived this holistic view of physiology through the identification of inter-organ communications that are unanticipated, functionally important, and would have been difficult to uncover otherwise. This Review highlights this point by showing how two tissues usually not seen as endocrine ones, bone ...
متن کاملBone Health in Endocrine Diseases Associated with Androgen Excess: A Narrative Review
Introduction: Osteoporosis is humans' most common bone tissue disease that causes bone fractures. Based on the evidence, a combination of genetic and environmental factors, hormonal disorders such as estrogen deficiency, malnutrition, inflammatory factors, drugs, and physical inactivity are related to the pathogenesis of this disease. The present study aimed to review the effects of androgens a...
متن کاملBone Regulates Glucose Metabolism as an Endocrine Organ through Osteocalcin
Skeleton was considered as a dynamic connective tissue, which was essential for mobility, calcium homeostasis, and hematopoietic niche. However more and more evidences indicate that skeleton works not only as a structural scaffold but also as an endocrine organ, which regulates several metabolic processes. Besides osteoprotegerin (OPG), sclerostin (SOST), and Dickopf (DKK) which play essential ...
متن کاملAn investigation on some toxic effects of pyriproxyfen in adult male mice
Objective(s): Pyriproxyfen as an insect growth regulator is widely used globally for pest management. There are reports on adverse effects of insecticides such as organ toxicity, endocrine disruptions, and teratogenicity in animals and humans. We aimed to investigate reproductive toxicity of pyriproxyfen in adult male mice.Materials and Methods:</stro...
متن کاملRegulation of male fertility by bone.
A broadly held view of bone is that it is a tissue defined by its mechanical and scaffolding properties, whose interaction with other organs of the body is similar to that exerted by an armor protecting them. In the last 10 years, using mouse genetics, this view of bone as an assembly of inert calcified tubes has considerably evolved to a much more dynamic picture. It is now clear that the skel...
متن کامل